View modes
There are several view modes available - most of them will change the layout and/or options that are available in the ui. There is e.g. a Command & Conquer mode where you can manage the normals that are part of the vxl.
Ace of Spades is another view mode that e.g. doesn't offer a Do-you-want-to-resize popup for the vxl maps.
Artists that only want to edit voxels without animating them might use the simple layout to get a less complex ui.